This free Ableton Live device makes images into wavetables

Standard

It’s the season of the wavetable – again. With Ableton Live 10.1 on the horizon and its free Wavetable device, we’ve got yet another free Max for Live device for making sound materials – and this time, you can make your wavetables from images.

Let’s catch you up first.

Ableton Live 10.1 will bring Wavetable as a new instrument to Standard and Suite editions – arguably one of the bigger native synth editions to Live in its history, ranking with the likes of Operator. And sure, as when Operator came out, you already have plug-ins that do the same; Ableton’s pitch is as always their unique approach to UI (love it or hate it), and integration with the host, and … having it right in the box:

Ableton Live 10.1: more sound shaping, work faster, free update

Earlier this week, we saw one free device that makes wavetables for you, built as a Max for Live device. (Odds are anyone able to run this will have a copy of Live with Wavetable in it, since it targets 10.1, but it also exports to other tools). Wave Weld focuses on dialing in the sounds you need and spitting out precise, algorithmic results:

Generate wavetables for free, for Ableton Live 10.1 and other synths

One thing Wave Weld cannot do, however, is make a wavetable out of a picture of a cat.

For that, you want Image2Wavetable. The name says it all: it generates wavetable samples from image data.

This means if you’re handy with graphics software, or graphics code like Processing, you can also make visual patterns that generate interesting wavetables. It reminds me of my happy hours and hours spent using U+I Software’s ground-breaking MetaSynth, which employs some similar concepts to build an entire sound laboratory around graphic tools. (It’s still worth a spin today if you’ve got a Mac; among other things, it is evidently responsible for those sweeping digital sounds in the original Matrix film, I’m told.)

Image2Wavetable is new, the creation of Dillon Bastan and Carlo Cattano – and there are some rough edges, so be patient and it sounds like they’re ready to hear some feedback on how it works.

But the workflow is really simple: drag and drop image, drag and drop resulting wavetable into the Wavetable instrument.

Okay, I suspect I know what I’m doing for the rest of the night.

Image2Wavetable Device [maxforlive.com]

The post This free Ableton Live device makes images into wavetables appeared first on CDM Create Digital Music.

from Create Digital Music http://bit.ly/2ElIxfA
via IFTTT

Researchers genetically modify yeast to ‘brew’ THC and CBD

Standard

Scientists in California have created a cheaper, safer, environmentally-friendly way to produce cannabinoids, the chemical compounds that give cannabis its many medicinal (and mind-altering) qualities. The trick is in using genetically modified brewer’s yeast to produce cannabinoids, rather than ethanol, according to research published today by the University of California, Berkeley.

The researchers identified more than a dozen genes — including many used by the cannabis plant to synthesize cannabinoids — and inserted them into the yeast. The genes create enzymes that start a series of chemical reactions, and in a process much like brewing beer, those reactions turn sugar into cannabigerolic acid. From that, a long list of cannabinoids can be produced, including THC and CBD, the latter of which you can now find touted as a cure-all at your local gas station.

In all seriousness, CBD, or cannabidiol, is used to treat childhood epileptic seizures and may potentially treat Parkinson’s disease, chronic pain, anxiety and more. THC is now in FDA-approved medications for chemotherapy-induced nausea and to improve appetite in AIDS patients. But medical marijuana research has been slowed by the fact that the more than 100 other chemicals in the plant occur in small quantities. The scientists behind this new, genetically-modified yeast say it could speed up production of these chemicals, theoretically advancing the pace of cannabinoid research and pharma development.

Several other chemicals and drugs are already produced using genetically modified yeast. Those include human growth hormone, insulin and blood clotting factors, and yeast production comes with many benefits. In this case, the yeast requires less water than cannabis, and it can be produced without the pesticides, fertilizers and energy-zapping lights and ventilation systems often used in the plant’s cultivation.

Via: The Guardian

Source: UC Berkeley

from Engadget https://engt.co/2GVdFqf
via IFTTT

Google’s DeepMind can predict wind patterns a day in advance

Standard

Wind power has become increasingly popular, but its success is limited by the fact that wind comes and goes as it pleases, making it hard for power grids to count on the renewable energy and less likely to fully embrace it. While we can’t control the wind, Google has an idea for the next best thing: using machine learning to predict it.

Google and DeepMind have started testing machine learning on Google’s own wind turbines, which are part of the company’s renewable energy projects. Beginning last year, they fed weather forecasts and existing turbine data into DeepMind’s machine learning platform, which churned out wind power predictions 36 hours ahead of actual power generation. Google could then make supply commitments to power grids a full day before delivery. That predictability makes it easier and more appealing for energy grids to depend on wind power, and as a result, it boosted the value of Google’s wind energy by roughly 20 percent.

Not only does this tease to how machine learning could boost the adoption of wind energy, it’s also an example of machine learning being put to good use — solving critical problems and not just jumping into your text thread to recommend a restaurant when you start talking about tapas. For DeepMind, it’s a high-profile use of its technology and proof that it’s not only useful for beating up professional StarCraft II players.

Source: Google

from Engadget https://engt.co/2H3u2Aa
via IFTTT

Creating the Photograph: Mary Ann Wamboldt’s “Pink Kiss”

Standard

Photographer Mary Ann Wamboldt is an Ontario based creative that shoots weddings, portraits, and a number of other things including travel photography. She’s been published a number of times and has won even more awards for her work. So when she submitted "Pink Kiss" to our Creating the Photograph series, we were very intrigued. The photo doesn’t have a whole lot of post-production and instead focuses more on in-camera techniques and lighting to get the look that we see. There isn’t any sort of post-production trickery or layer upon layer–instead there is just Mary Ann’s own creativity and technical know how. Here’s how she got the shot.

from The Phoblographer http://bit.ly/2NzAcsR
via IFTTT

The Cure drummer Andy Anderson dies aged 68

Standard

“We are blessed to have known him.”

Andy Anderson, former drummer for The Cure, has died. One of the band’s founders, Lol Tolhurst, announced that Anderson died peacefully at home yesterday afternoon (February 26).

Anderson was diagnosed with stage 4 terminal cancer earlier this month. “I’m totally fine and aware of my situation I’ve gone for a no resuscitation”, he said in a Facebook post. “No Boo, Hooing, here, just be positive, for me it’s just another life Experience and Hurdle.”

Andy Anderson recorded with The Cure on the albums Japanese WhispersThe Top and Concert. His first official appearance for the band was on the single ‘The Lovecats’.

He also recorded and collaborated with a variety of artists, including The Gun Club, Jason Donovan, Peter Gabriel, Isaac Hayes, Iggy Pop, Mike Oldfield and Midge Ure.

Watch next: Watch Nabihah Iqbal cover The Cure’s classic ‘A Forest’

The post The Cure drummer Andy Anderson dies aged 68 appeared first on FACT Magazine: Music News, New Music..

from FACT Magazine http://bit.ly/2GPGmEQ
via IFTTT

We compared the Samsung Galaxy Fold with the Huawei Mate X — and the winner was clear

Standard

Huawei Mate X vs Samsung Galaxy Fold

  • We compared the Samsung Galaxy Fold with the Huawei Mate X.
  • The folding phones are one of the biggest innovations in the smartphone market for years, and were the main talking point at Mobile World Congress 2019.
  • Watch the video below to see which one came out on top.

 

Full transcript below:

Shona Ghosh: We are at Mobile World Congress 2019 in Barcelona it’s the biggest global conference for mobile in the world and it’s pretty exciting because Huawei has now launched its own foldable phone, The Mate X and that’s a few days after Samsung also launched a foldable phone called The Galaxy Fold.

We’re gonna put the two phones head to head, talk about the specs, the price, availability and give you an early verdict about which phone might be better.

So the Samsung Galaxy Fold is the smaller of the two devices.

If folded in and being used as a smartphone, the screen measures 4.6 inches. It’s good for people who maybe like those smaller screens.

A slightly different story when you unfold The Galaxy Fold and then that’s a 7.3 inch screen, and that’s like a small tablet or an e-reader, again quite a nice size for traveling and for people who don’t really like those jumbo screens.

As always with Samsung phones the display is quite sharp, it’s pretty good, comparable to another Galaxy phone.

We had a bit more of a chance to see the Huawei Mate X close up and we could see the screen was pretty impressive from what little time we had with it.

It’s a much bigger proposition as a device so folded up as a smartphone the Mate X is 6.6 inches, which is huge, that’s actually a jumbo phone really.

Unfolded it becomes quite a nice size tablet which is eight inches.

Huawei device from what we’ve seen, looks a little bit smoother.

Samsung interestingly isn’t showing anyone what The Galaxy Fold looks like up close, so as far as I know no reporters, no analysts, have had a chance to play with The Galaxy Fold.

Now obviously Samsung says that the phone is super durable, it can withstand kind of falls, and that it’s quite tough, but you know we’d need some real-world proof that that’s actually the case.

So in terms of a real world, you know, how the phones perform in the real world, I think Huawei’s a little bit ahead of Samsung on this one.

And what’s a little bit troubling is that Samsung’s phone is due to come out in a couple of months but no one’s really seen properly how the device works.

Another key difference with The Mate X is that there’s no notch on the screen when the Mate X has folded out.

The way Huawei has got around the camera problem, is that it’s coasted it’s camera on Samsung’s on the side of the device, on a sort of dedicated sidebar.

Now that adds a tiny bit of bulk to the device, when it’s folded out, it otherwise looks very slim, but the advantage is that you can hold that kind of sidebar where the cameras are and sort of grip while you’re holding the tablet, that works quite nicely, and then you know when the tablet folds back in, you know the camera array is still visible on the side and you can still use it like any normal smartphone.

The Galaxy Fold has a lot of cameras. There are six cameras on the device in total, which is a lot of cameras.

The reason is because you’re obviously going to be taking photos when you use the device in different configurations.

We don’t know too much about the Huawei Mate X’s camera setup, we know that there are three or possibly four cameras on the back.

The suspicion is that there is, in fact, a fourth camera lens in the back of the device, that Huawei’s gonna reveal at some later date, when it reveals its next batch of phones. Both phones have quite powerful batteries.

The Mate X has a 4500 milliampere battery while The Samsung Galaxy Fold has a 4380 milliampere battery, what we don’t know just yet is exactly what that translates to in the real world with real use, you know whether they’ll have a day’s full charge or possibly more.

So for me one major point to think about is how thick these devices are going to be because obviously when they’re folded up both The Huawei Mate X and The Samsung Galaxy Fold are gonna be thicker than your average smartphone.

We don’t know how thick The Samsung Galaxy Fold is going to be, Samsung hasn’t really talked about the, the weight or the thickness.

When you’ve folded the device back up into smartphone mode, it doesn’t quite fold flat, it’s not completely flat when you fold it up, so that slightly creates sort of an extra bulk.

For me it sounds like The Huawei Mate X is probably thinner than The Galaxy Fold because The Mate X folds in a really flush way, it’s something Huawei were really keen to emphasize.

There’s, is that the tablet is completely flat and then when folded it folds in a really nice neat way and there’s no gap between the screens when it’s folded up.

One major drawback of the new Galaxy Fold and The Mate X is that they are extremely expensive, so everyone was outraged when Apple introduced the $1,000 iPhone, now the game has changed considerably with the arrival of folding smartphones which cost about double that price.

An early verdict that I would give is that the Huawei Mate X is probably the superior device.

It just looks much more finessed, it just looks like Huawei has spent a little bit more time working on that hinge mechanisms to make the folding and unfolding really really smooth.

The display looks absolutely phenomenal. Galaxy Fold looks really impressive too, it sounds like the cameras are highly impressive.

For me the much bigger question is whether anyone actually wants a folding phone, there hasn’t been a huge amount of consumer demand for flexible displays it’s something that’s really been driven by the industry it feels like and you know, it’s sort of it’s arrived for the mainstream audience, but whether the mainstream audience takes it up I’m not so sure.

Each phone costs a lot of money, so you really wanna think about whether you truly wanna drop a couple of thousand pounds, euros, dollars, on a device like that before you go out and buy one at the shop.

Join the conversation about this story »

NOW WATCH: Amazon will pay $0 in federal taxes this year — here’s how the $793 billion company gets away with it

from SAI https://read.bi/2VqLzWK
via IFTTT

This ER doctor is about to debut the first marijuana breathalyzer, and he’s already raised $34 million from investors including the creator of ‘Law & Order’

Standard

hound labs breathalyzer 2

  • California startup Hound Labs is getting ready to roll out the world’s first marijuana breathalyzer.
  • The device will be tested in pilot programs with law enforcement and a labor union, and will work similarly to an alcohol breathalyzer.
  • Based in Oakland, Hound Labs has raised $34 million in funding and has notable investors like Dick Wolf, the creator of hit TV series ‘Law & Order.’
  • While there’s currently no well-defined legal way to determine if someone is too high to drive, regulators have outlined some possibilities. Today, police rely on subjective measures like field sobriety tests.

Emergency room physician and deputy sheriff Mike Lynn wasn’t at work when the idea for a marijuana breathalyzer came to him.

Instead, the 52-year-old father of four had been cycling with a friend in the leafy hills of Oakland, California when the pair were passed by a speeding car. Plumes of skunk-scented smoke trailed the vehicle from the driver’s side window.

The friend — a professional race car driver — told Lynn he’d never dream of driving under the influence of marijuana. And in that moment, Lynn decided there had to be a way to stop others from doing so.

So in 2014, Mike and his wife Jenny created Hound Labs, a startup headquartered in downtown Oakland. Their first product would be the world’s first device capable of detecting recent cannabis use on a person’s breath. It’s set to roll out this fall, when it will undergo pilot testing with an undisclosed division of law enforcement and with a nonprofit trade union that represents more than half a million construction workers in Northern California.

Hound Labs has raised $34 million so far, helped in part by notable individual investors including Dick Wolf, the creator and executive producer of the hit television series "Law & Order." Benchmark Capital, the Silicon Valley venture firm that made early bets on Uber, Snap, Dropbox, and WeWork, has also backed the company, along with Icon Ventures, the firm behind virtual healthcare company Teladoc.

Still, the company is up against some challenges.

There is currently no clearly-defined legal limit for driving after using marijuana and the science on cannabis use and driving remains in its early stages. In addition, the company has not published any of its clinical trials, although it said one is currently awaiting publication. Finally, it remains to be seen how Hound Labs’ device will impact marijuana policing, which research suggests has been influenced by racism.

‘There’s got to be a way to solve this’

hound labs Mike LynnIf anyone were to create a marijuana breathalyzer, it would probably be Mike Lynn. An active SWAT team member and reserve deputy sheriff as well as a professor of emergency medicine and former biotech venture capitalist, Lynn has worked in nearly every field touched by the burgeoning industry of legalized cannabis.

It was while working as a partner at $36 billion private equity firm Adams Street Partners, where he specialized in medical devices and biotech, that Lynn decided to dedicate his time to the breathalyzer. Over and over during his free time while cycling, he’d get passed by speeding drivers whom he suspected of smoking weed.

"That just got me thinking, there’s got to be a way to solve this. Just like there is for alcohol," Lynn told Business Insider.

Dozens of drug tests exist that can tell you if someone has used marijuana in the last several days to weeks by looking for THC (marijuana’s main psychoactive ingredient) in blood and urine. But none of these tests show whether someone has used recently — that is, whether someone is currently high. 

Read more: Here’s how long various drugs stay in your body

Pot reaches its peak levels in the brain and body between two and three hours after smoking. That is also the time at which federal regulators like those at the National Highway Traffic Safety Administration say someone is likely to be the most impaired by cannabis.

For Lynn’s breathalyzer to be useful, it needed to identify recent marijuana use and thus meet regulator’s standards for determining whether or not someone was high. 

That turned out to be a difficult problem to solve. THC is present in extremely low concentrations in breath. So he and his team of four scientists — which includes a Stanford lung specialist as well as a bioengineer and a chemist from UC Berkeley — got to work. Since 2014, they’ve prototyped nearly 80 versions of their device, which works somewhat similarly to a standard alcohol breathalyzer with a couple of key differences.

"It came down to finding the needle in 10,000 haystacks," Lynn said.

Lynn said they’ve tested the technology in two clinical trials with scientists at the University of California, San Francisco. One, presented as a poster session at laboratory science conference Pittcon, used an early version of Hound Labs’ device and came away with mixed results. The next used the current version of the device and came away with better results, Lynn said. The work has not yet been published, but Hound Labs shared a summary with Business Insider.

"The ability to capture breath and measure such low concentrations of molecules represents a significant breakthrough," Kara Lynch, the lead author on the latest study and an associate professor of laboratory medicine at UCSF, said in a statement.

"We hope to continue to collaborate with Hound Labs on clinical studies to advance the field of breath diagnostics," she added.

How Hound Labs’ marijuana breathalyzer works

hound labs breathalyzer 1Driving high is currently against the law nationwide and can be treated the same as driving drunk. But unlike with alcohol, where there’s a clearly-defined legal limit for how much you can drink and drive, no such limit for pot exists.

As legalization efforts spread across the country, that’s likely to be a hot issue.

To use Hound Labs’ device, someone blows into it for roughly a minute. Then, using a special type of biochemical test to measure the recent presence of THC, the device returns a positive or a negative result. 

"If somebody has it on their breath, that means they absolutely used pot within the last couple of hours," Lynn said.

Still, experts have yet to nail down precisely what it means to be too high to drive.

The science on how cannabis affects driving remains somewhat unclear, in large part because few studies on weed and driving have been conducted. The studies we do have suggest that marijuana blunts several skills involved in being behind the wheel.

Read more: Two studies on the effects of marijuana on drivers have completely different results

People who are high exhibit slower reaction time, worse motor coordination, and issues with attention and decision-making. Yet research also suggests that regular weed users are more likely to be aware of these effects and act accordingly, something that could make it tricky to set a universal standard for being too high to drive. Plus, unlike alcohol, cannabis has not been linked with aggressive or violent behavior.

Instead when it comes to cannabis, police rely on subjective measures of sobriety.

They do what are called field sobriety tests, for example, exercises where someone is directed to do something like follow an officer’s finger with their gaze or balance on one leg. An officer could also bring someone into a station to run a blood-based drug test, but those are slow to process and can’t necessarily show that a person was driving under the influence.

"Right now we don’t have a legitimate test for people going on the road under the influence of marijuana," William B. Evans, the former Commissioner of the Boston Police Department and currently the chief of police for Boston College, told Business Insider. Evans got a demo of the device after Lynn reached out to him, he said.

The subjectivity involved in marijuana policing could also play a role in a bigger problem that Lynn and Evans think Hound’s device may help curb: racial discrimination.

‘Something that nobody else can do right now’

marijuana, weedStatistics on marijuana and police arrests suggest that racism plays a strong role in the policing of cannabis, and it remains to be seen whether Hound Labs’ device will impact that.

While government surveys suggest that black people and white people use marijuana at similar rates, a recent New York Times investigation concluded that black residents of New York City were arrested at eight times the rate as white residents. Latino people were arrested at five times the rate of white people, the report found.

The disparity exists in other cities as well. Across the country, marijuana use appears to be roughly equal among black people and white people, yet black people are nearly four times as likely to be arrested for marijuana possession as whites, according to a recent report from the American Civil Liberties Union.

Lynn thinks his device could help both officers and drivers by giving them an objective way to measure impaired driving.

"If you do get pulled over and you’re a member of a minority community, you now have something objective that you can point to," he said.

Evans agreed. 

"People get killed by people driving under the influence no matter what nationality or race they are," Evans said, adding, "tools like this are going to be how we stop that."

Now that Hound Labs has suggested it has the science to make their breathalyzer useful, there appears to be significant interest in the device. Hound Labs is currently courting two major buyers of the tool, Lynn said.

The first is an undisclosed division of law enforcement that’s interested in using the devices to stop stoned drivers. The second is the Carpenters 46 Northern California Counties Conference Board, a trade union that represents more than half a million construction workers. Its goal is to ensure that employees are allowed to use marijuana off-duty while also making sure they’re not high on the job.

Read more: The number of people testing positive for marijuana in workplace drug tests is exploding, particularly in public safety and national security roles

Bill Feyling, the executive director of Carpenters 46, told Business Insider it planned to use the devices in a pilot project with a limited number of employers, where it will be able to test the devices in the field.

"We anticipate it’s going to be a successful test period," Feyling said.

SEE ALSO: After you spit into a tube for a DNA test like 23andMe, experts say you shouldn’t assume your data will stay private forever

DON’T MISS: A pair of high-profile Stanford scientists wants to use marijuana to treat an entire class of diseases where big pharma has fallen short

Join the conversation about this story »

NOW WATCH: How long you can stay in extremely cold temperatures before getting frostbite

from SAI https://read.bi/2GQdb4q
via IFTTT

Scientists just made marijuana compounds in a lab for the first time, and it could open the door to new treatments for devastating diseases

Standard

marijuana, weed

  • Scientists at the University of California at Berkeley have for the first time created cannabis compounds in a lab, instead of by harvesting them from a plant.
  • They detailed their work, which uses synthetic biology, in a study published Wednesday in the journal Nature.
  • If the technique can be scaled, it could transform the marijuana industry by allowing scientists to explore little-known cannabis compounds and manufacture those like THC and CBD for less money.
  • Several other startups have announced similar efforts, but none has demonstrated publicly that it has a technique that works.

Lab-made marijuana is coming.

In a move that’s expected to transform the marijuana and pharmaceutical industries, scientists at the University of California at Berkeley announced on Wednesday that they had for the first time created cannabis compounds in a lab, instead of by harvesting them from a plant.

If the technique can scale, it could pave the way for making marijuana’s therapeutic components more quickly and efficiently, for a fraction of the cost of traditional methods.

Using an increasingly popular approach known as synthetic biology, the researchers genetically engineered yeast to churn out a key component of marijuana that’s a precursor to two of the best-known compounds in the plant: THC and CBD. Using those precursors, they made the compounds themselves — no farm or field required.

While THC is the part of marijuana that causes a high, CBD has an emerging reputation as a therapeutic and is the active ingredient in the first federally approved marijuana-based medication. Thanks to the health and wellness uses that CBD is tied to, the market for the compound could reach $16 billion by 2025, up from perhaps $1 billion or so now.

Marijuana plants contain a host of other, little-known compounds that scientists suspect also carry therapeutic properties. But it’s been too difficult to produce them in large enough quantities to study.

That could now be set to change.

In a paper published in the journal Nature, the Berkeley researchers outlined how both types of marijuana compounds — the well-known ones like THC and the lesser-known ones like THCV — could be made in a lab. That’s likely to have big implications for startups and pharmaceutical companies that want to make new marijuana-based drugs for everything from epilepsy to pain and arthritis.

Several companies are working on similar efforts. Wall Street has noticed as well, saying that lab-made marijuana is one on a growing list of factors helping to accelerate cannabis’ entry into the pharmaceutical and consumer-wellness industries.

"There could be whole host of new products that could come from this," Jay Keasling, a UC Berkeley bioengineer who led the study, told Business Insider.

‘A critical step in the pathway that no one’s had until this point’

weed grinder

Before they could make marijuana compounds without a field or a greenhouse, Keasling and his team had to go hunting for the ingredients required to make it work in a laboratory — something of a holy grail for the cannabis industry.

Lab-made marijuana could have multiple advantages over traditionally grown marijuana, like a lower cost and a smaller environmental footprint.

Several companies are interested in becoming the first to prove that the method, also known as biosynthesis, works, including Ginkgo Bioworks, a synthetic-biology startup in Boston; Intrexon, a biotech in Maryland; and Hyasynth Bio, a Canadian startup.

Wall Street is keen to see it happen too.

"Compared to chemical methods, biosynthesis methods are more cost-effective, scalable, and environmentally friendly," analysts at the investment firm Cowen said in a note circulated this week.

Keasling and his team spent years figuring out how to do it.

They uncovered a clue in the patent literature about a way to tweak the genes of yeast using marijuana DNA that would result in it churning out a key precursor to CBD and THC.

The process of modifying the DNA of a basic organism like yeast or E. coli to coax it into producing another product is known as synthetic biology. In recent years, investors have been pouring money into companies in the area.

Put simply, synthetic biology involves harnessing the power of cells to make things like drugs, biodegradable building materials, and less toxic sweeteners for food.

Read more: A Silicon Valley startup with 26 patents under its belt just raised $400 million from SoftBank and Goldman Sachs to make materials from living things

So Keasling and his team took all the basic ingredients identified by previous researchers — components of yeast DNA and components of cannabis DNA — and tried to make the marijuana compounds in a lab. Several attempts failed.

"We tried all the tricks we had," Keasling said. "We just could not get it to work."

So they took another stab at it. After several years of work exploring hundreds of marijuana genes, they were able to home in on their target: an enzyme called CsPT4. It allowed them to make the ingredients they needed to then make compounds like CBD and THC.

"This is a critical step in the pathway that no one’s had until this point," Keasling said.

A startup that wants to make new drugs and sign deals with pharma

marijuana cannabis pot weed bud nug medical

The next step for Keasling is scaling up. To do that, he must prove in larger experiments that his technique works and at a lower cost than traditional manufacturing.

That could be of major interest to pharmaceutical companies like GW Pharma, which recently became the first company with a US-approved marijuana-based drug. (Called Epidiolex, the drug is designed to treat rare forms of epilepsy using high concentrations of CBD.)

It might also interest several startups that in recent years have pledged to turn marijuana compounds like CBD into federally approved drugs for diseases like Crohn’s and multiple sclerosis.

Read more: A pair of high-profile Stanford scientists wants to use marijuana to treat an entire class of diseases where big pharma has fallen short

Keasling has already licensed the technology he described in the study to a startup he founded in 2015 called Demetrix. He said it would be open to working with a range of established companies in the pharmaceutical industry or the food industry.

Jeff Ubersax, Demetrix’s CEO, told Business Insider that the startup had raised $11 million in venture capital led by Horizon Ventures, a VC firm in Hong Kong. Horizon has also backed Impossible Foods, the company behind a plant-based burger, and Siri, the developer of Apple’s virtual assistant.

No stranger to startups, Keasling has founded several companies and is as an adviser to four. In 2003, he helped found Amyris, now a skincare company, and in 2010 he founded Lygos, a startup that wants to use microbes for renewable-energy purposes. He’s no longer involved with Amyris but remains an adviser to Lygos.

Read more: After a kick-start from Bill Gates, a Silicon Valley company aims to be the ‘Intel Inside’ of the $200 billion sweetener and skincare market

With Demetrix, Keasling and Ubersax are focused on two goals, they told Business Insider.

They want to churn out lab-made versions of cannabis’ well-known compounds. They also want to make a handful of understudied marijuana compounds, ingredients Keasling said are likely to have therapeutic properties; THCV, for example, could have appetite-staunching potential.

Other startups have similar goals. Ginkgo Bioworks recently signed a $122 million deal with the Canadian marijuana producer Cronos to make the well-known cannabis compounds and the lesser-known ingredients, using the same synthetic-biology principles.

Keasling said he thinks he can make marijuana compounds for a fraction of the cost of traditional cannabis production because his method wouldn’t require greenhouse-building materials, large amounts of land or water, or manual labor.

"From a scientific perspective, with all the rare cannabinoids we’re going to be able to produce, I think it’s going to be really cool," Keasling said.

SEE ALSO: A startup with ties to Bayer has inked a $122 million deal to make lab-grown marijuana — and it’s eyeing the pharma industry

READ MORE: A Silicon Valley startup with 26 patents under its belt just raised $400 million from SoftBank and Goldman Sachs to make materials from living things

Join the conversation about this story »

NOW WATCH: The polar vortex striking the US will cause temperatures to plummet up to 40 degrees colder than normal

from SAI https://read.bi/2EmV9mP
via IFTTT

Lady Gaga talks about *that* Oscars performance with Bradley Cooper

Standard

TwitterFacebook

Lady Gaga and Bradley Cooper’s utterly breathtaking performance of "Shallow" at the Oscars really had the internet talking, but as Gaga reiterated on Jimmy Kimmel Live! on Wednesday, it is very much an act.

"Quite frankly, social media is the toilet of the internet. What it has done to pop culture is abysmal," Gaga told the show (from 3:15).

"People saw love, and guess what, that’s what we wanted you to see. This is a love song, ‘Shallow.’ The movie, A Star Is Born, is a love story."

Gaga added they both had worked on the performance all week, and Cooper as director made decisions like making sure the audience was lit throughout the song, among other details that helped with the illusion of love. Read more…

More about Entertainment, Tv, Television, Lady Gaga, and Bradley Cooper

from Mashable! http://bit.ly/2T76Loc
via IFTTT

Full Moon and Eclipse Photography: Your Guide to Where They Are in 2019 and How to Capture Them Effectively

Standard

The post Full Moon and Eclipse Photography: Your Guide to Where They Are in 2019 and How to Capture Them Effectively appeared first on Digital Photography School. It was authored by Caz Nowaczyk.

Full moons and eclipses are a unique time to capture some interesting photographs.

Full Moons

Full moons usually happen once a month, with the occasional second full moon falling in the same month. This second full moon is called a Blue Moon.

Solar and Lunar Eclipses

A solar eclipse happens when the new moon passes between the earth and the sun, casting a shadow over the sun.

A lunar eclipse occurs when the earth passes between the full moon and the sun, causing the moon to fall into earth’s shadow. Lunar Eclipses occur only at the full moon.

To give you the opportunity to shoot the moon, below is a calendar of Full Moons and Eclipses for 2019, followed by some articles that will help you to capture the moon or eclipse effectively.

Full Moon and Eclipse Calendar

Full Moons

New York, N.Y (US/Eastern)

Date Time
Jan 21 00:17
Feb 19 10:53
Mar 20 21:43
Apr 19 07:12
May 18 17:11
Jun 17 04:31
July 16 17:39
Aug 15 08:31
Sep 14 00:35
Oct 13 17:10
Nov 12 08:37
Dec 12 00:14

Eclipses

Date Type
July 2 Total Solar Eclipse
July 16 Partial Lunar Eclipse
Nov 11 Mercury Transit
Dec 26 Annular Solar Eclipse

 

Full Moons

Sydney, Australia (AEST)

Date Time
Jan 21 00:17
Feb 20 02:53
Mar 21 12:42
Apr 19 21:12
May 19 07:11
Jun 17 07:38
July 17 17:38
Aug 15 22:29
Sep 14 14:32
Oct 14 08:07
Nov 13 00:34
Dec 12 16:12

Eclipses

Date Type
July 17 Partial Lunar Eclipse

 

Full Moons

London, England, UK

Date Time
Jan 21 05:16
Feb 19 15:53
Mar 21 01:42
Apr 19 12:12
May 18 22:11
Jun 17 09:30
July 16 22:38
Aug 15 13:29
Sep 14 05:32
Oct 13 22:07
Nov 12 13:34
Dec 12 05:12

Eclipses

Date Type
July 16-17 Partial Lunar Eclipse
Nov 11 Mercury Transit

 

How to Achieve Better Full Moon and Eclipse Photography

20 Dos and Don’ts for Shooting the Moon

Beyond Full Moon Photography

Moon Photography: 6 Tips for Better Moon Photos

How to Photograph a Solar Eclipse

Tips for Photographing a Lunar Eclipse

How to Photograph a Lunar Eclipse

 

 

The post Full Moon and Eclipse Photography: Your Guide to Where They Are in 2019 and How to Capture Them Effectively appeared first on Digital Photography School. It was authored by Caz Nowaczyk.

from Digital Photography School http://bit.ly/2Tj77Y2
via IFTTT