Watch Paintings Come to Life and Chase Each Other Around in an Art Gallery

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Filip Sterckx’s Gallery Invasion is a clever, kooky, and totally adorable art show that brings art works to life through projection mapping. It’s like those Night at the Museum movies but with drawings deciding to jump out of their canvas and play rough with each other all over the gallery instead of museum exhibits messing with Ben Stiller for some reason. But it’s a lot of fun to see the artwork appear self-aware and interact with its surroundings.

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These Pictures Of People Before And After Quitting Drinking May Make Me Reconsider Getting Blind Drunk This Afternoon

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sober-8

Bored Panda

4 years sober ^

We all know “technically” drinking is bad for you. Excessive drinking can damage the heart, interfere with the brain’s communication pathways, destroy the liver, and weaken the immune system.

*Slowly puts down Steel Reserve*

I’d argue, however, that the damage drinking does to one’s body is peanuts in comparison to the damage everyday life does on the sober person. There is not one scenario on the planet where drinking doesn’t enhance one’s experience. Besides running. And running sucks so that doesn’t count. And drinking is as big as a social lubricant as it is a stress reliever. Personally, I cannot stop drinking because then I wouldn’t have any friends. They are degenerates. But they are my degenerates, and for that reason, cheers.

But some people, better people than I, have the self-restraint to stop drinking to “get healthy” and “invest in their future” and “stop a downward spiral.” These people have shared before and after pictures of their journey to soberdom and for a second I thought about thinking about not drinking tonight.

Compiled by Bored Panda:

8.5 Months Sober

sober-22

Bored Panda

300 Days Sober

sober-34

Bored Panda

1 Year Sober

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99 Days Sober 

sober

Bored Panda

500 Days Sober

sober

1 Year Sober

sober-2

6 Months Sober

sober-3

Both 3 years, 4 months, 17 days sober

sober-5

1 Year Sober

sober-6

Props to all these people who overcame their addictions for themselves and the people they love.

For the rest of you, tryna get blind drunk tonight?

Check out some more success stories over at Bored Panda

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These modular hurricane-proof homes cost less than $200,000 to build

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cubicco house rendering 1
Courtesy
of Cubicco

Dutch company Cubicco has created a flat-pack, modular,
prefabricated, hurricane-proof home that can be built for
less than $200,000. And it could soon come to the Caribbean
and Florida.

The Cubicco home, which is made up
of laminated wood and cork
, is designed to hold up to the
high-velocity hurricane codes
in Florida’s Miami-Dade County. That means buildings
must be able to withstand 185 mph winds, have impact-resistant
glass, and be elevated off the ground. Other parts of the
home, including hurricane-rated windows and doors, layers of
plywood sheathing, and insulation, give it
additional hurricane resistance.

The units can be stood on stilts, moved around and
disassembled. Because the homes are prefabricated,
building crews can simply get trained to assemble the
Cubicco units, get the parts shipped to a desired location, and
complete construction in a few months. The structures’ modular
design also means they can be combined into small villages
or larger homes.

The homes have a few optional bells and whistles to increase
sustainability as well, including a water reclaiming system,
spots for solar panels on the roof, and open slats that
allow for geothermal heating and cooling.

The price for construction is generally below $200,000 before
finishes, flooring, and appliances, though it depends on
square footage. The company says that units usually cost
about $175 per square foot to construct.

It’s a high-tech, almost IKEA-like solution to housing, a
“future-proof” home that can withstand tropical storms and
usher people toward a more sustainable lifestyle.


cubicco porch
Courtesy
of Cubicco

The company has already sold some individual homes to customers
in Florida, but this week, it will begin work on its first group
housing development in the Caribbean. Cubicco designer Marcio
Gomes da Cruz tells Business Insider that the company has
residential projects underway in the Bahamas and Turks
and Caicos. 

Cubicco is an appealing model on those islands for several
reasons. First, the designs are built to be hurricane resistant,
a definite plus given how badly
Haiti was recently hit
by Hurricane Matthew. Second, the
prefabricated construction process is more convenient since
some materials can be hard to come by in island locations.
And third, the construction doesn’t create a lot of
waste, which is an important consideration in
places without much landfill space. 

“Disposal is very expensive in the Caribbean — when you want to
get rid of a dumpster full of construction debris, it’s kind of
an issue,” da Cruz says. 

Da Cruz won’t yet say where the specific
developments are located, or how many units will be in
each project. But he says the company expects to finish them in
the next few months.

Cubicco is now focusing on large-scale projects like these,
and has stopped selling straight to individual
customers. Da Cruz says part of the reason is
that consumers generally look for the cheapest housing
available.

“Most people in Florida will come to us because they love
the idea and they love what we’re doing. But when it comes down
to dollars and cents, they don’t want to pay for it,” he says.
“They don’t want to pay for the additional installation. They
don’t want to pay for the water reclaiming system. So it’s the
kind of thing that, if you don’t care about the environment,
we’re not the company for you.” 

Cubicco’s design has been approved under Florida’s building codes
for modular units in Florida (which pertains
to everything but the foundation), but the homes cost more
than traditionally constructed houses because of their
sustainable, storm-resistant features.

“We are not affordable housing,” da Cruz says. “We’re a
higher end product that can be achieved for relatively decent
price per square foot.” 

So while some buyers in Florida are still ignoring climate warnings and
snatching up weather- and flood-susceptible properties,
Caribbean homeowners will soon get a new, more
disaster-proof option.

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Everyone is raving about male birth control — here’s when it might actually arrive

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time men last in bed thumbnails 06
Gene
Kim

Women get a short and complicated stick when it comes to family
planning.

Though birth control pills are 99% effective when taken
correctly,
free in the US
, and among the safest and most widely used
forms of contraception, there’s a lot to dislike, namely the
common side effects.

A lot of women on the pill or other hormone-based forms of birth
control experience acne, mood swings, depression, cramping,
nausea, vomiting, breast tenderness, bleeding between periods,
weight gain, and changes in sexual desire, to name a few things.
Some formulations can even lead to serious complications (though
very rarely) like blood clots, heart attack, stroke, liver
tumors, and gallstones,
according to Planned Parenthood
.

Meanwhile, men don’t have any FDA-approved pill, patch, implant,
shot, or other medicated form of birth control available to them.
The only safe and effective options are condoms, vasectomies
(which aren’t easily reversible), or abstinence. (Sorry, guys,
pulling out is
a very risky strategy
.)

If some oral or injectable drug could safely, reliably, and
temporarily reduce a man’s sperm fertility, then family
planning options could be more balanced — and millions of women
could breathe huge sighs of relief.

Thus the world
is in a tizzy
over a new study of a male birth control
injection, which appears to reversibly slow down sperm production
to a crawl.

The research, published October 27
in The Journal of Clinical Endocrinology and Metabolism, focused
on 320 male volunteers in steady relationships with female
partners. Researchers injected the guys with a two-hormone
cocktail, which was designed to suppress sperm formation, every
two months, for 13 months.

The injection was about 98% effective in preventing unwanted
pregnancies in the portion of men who responded to the hormones.
Furthermore, this infertility reversed within a year after
stopping injections for about 95% of volunteers.

As good as this may sound on paper, however, it may be years
before it makes its way to apothecaries or doctors’ offices.

The reason? A hodgepodge of cultural, bureaucratic, and
scientific issues stand in the way.

How the injection works


A nurse prepares a H1N1 flu vaccine shot at a hospital in Budapest, Hungary, in this November 20, 2009 file photo.  REUTERS/Karoly Arvai/Files
Thomson
Reuters

Most birth control methods for women exploit a natural moment of
infertility,
and reversibly so
: pregnancy.

By regularly taking the pill, which contains synthetic versions
of pregnancy hormones (like estradiol, a progestin, or both),
women can prevent ovulation, hinder implantation of a fertilized
egg, block sperm from reaching their eggs, or all
three
.

The new male birth control injection works a different route: by
cutting sperm production down to levels less than 1 million sperm
per milliliter, which are considered clinically infertile. (The
typical
fertile man
, according to the World Health Organization, has
about 15 million sperm per milliliter of semen, or 39 million
sperm per ejaculation.)

The injection uses two different synthetic hormones to get the
job done.

One is a
progestogen
, or class of hormones that help women
maintain a pregnancy
. In men they affect sperm development
and, quite literally,
whip the cells into a frenzy
.

The other hormone is a synthetic form of testosterone. Though
testosterone does a lot in the bodies of both men and women, it’s
best known for its boost to sex drive
in men
. But too much, as researchers learned in the 1980s and
1990s,
can slow down sperm production
— and so testosterone became a
prime target for male birth control.

Getting the dose correct emerged
as one issue
, though. While one concentration of testosterone
would slow sperm production in one man, it would not for another,
and inconsistency is something no one likes in their drugs. The
new study also notes there are concerns about significant
long-term side effects for taking high doses of synthetic
testosterone.

Luckily, scientists in the mid-2000s discovered that mixing
progestogens and testosterone provided a double-whammy to sperm
production, all while requiring less testosterone.

Trouble is, it wasn’t known how well the injection and reduced
sperm counts would work in the real world: during unprotected
sex.

What the new study discovered


pregnancy pregnant woman baby belly celebrity GettyImages 459679632

Getty
Images


The new study, penned by 16 researchers from all over the world,
ran from 2008 through 2012 in three phases.

Their idea was to test how regular progestogen-testosterone
injections worked on stable heterosexual couples who voluntarily
went off birth control.

Researchers set up 10 sites in seven different countries to
recruit men “aged 18-45 years, and their 18-to-38-year-old female
partners, in stable, monogamous relationships,” according to the
study. Volunteers were told there was a risk for pregnancy, too,
since the procedure was experimental.

The researchers ended up enrolling 320 male volunteers in the
first “suppression” phase: a round of four injections over 24
weeks, which shut down sperm production to 1 million cells per
milliliter (or less).

At least seven men (2%) didn’t see suppressed sperm production,
while dozens of other men dropped out. This left 266 volunteers
who responded and moved on to the second “efficacy” phase. Men
received injections once every 8 weeks for 56 weeks and didn’t
use condoms — all while their girlfriends or wives went off birth
control.

Due to a big and unexpected change in the study (more on this
later), plus additional dropouts, the researchers ended up with
111 men who fully completed this crucial phase.

Six men “rebounded” above of the 1-million-sperm cutoff over the
56-week period, and four couples got pregnant. If you
compare those pregnancies to all the time couples spent on male
birth control — again, not in combination with any female
contraception — it was about 97-98% effective
. That’s
pretty close to the 99% effectiveness seen with correct use of
the pill for women.

But the researchers also tested a big concern for male birth
control: a return to fertility.

Nearly 95% of men who received the injections bounced back to the
study’s measure of a fertile sperm count within a year. On
average, it took about half a year for the volunteers to spring
back in this third “recovery” phase of the study.

But eight men had trouble resuming fertile sperm counts. It took
five of them longer than a year to recover, with at least one man
taking 74 weeks. One man didn’t recover fertile sperm counts
within 4 years after his last injection, though it’s impossible
to know if the injections or some other problem led to that
result.

Either way, this hiccup matters. According to Susan Scutti’s
reporting for CNN on
the male birth control study
:

“It shows that it’s a risk, a low-probability risk of it, and
it’s not to be sneezed at as a risk of it, surely,” said
Elisabeth Lloyd, a faculty scholar at the Kinsey Institute,
professor of biology and an adjunct professor of philosophy at
Indiana University Bloomington. She is unaffiliated with the new
study.

That was just one issue with the study, though.

Counting the caveats

sperm and egg

No study is perfect, and this one had plenty of complications
that are important to consider.

For one, a sample size of 320 men — while seemingly large — is
not as ideal as studying, say, 5,000 or even 1,000 men. And
again, the injections didn’t work on some men, and a lot of men
dropped out of the study.

Second, if you live in the US you may be surprised to know that
all 10 of the study’s recruiting centers were out of the country.
Two sites each were located in “Australia, Germany, and United
Kingdom and 1 site [each] in Chile, India, Indonesia, and Italy,”
according to the study.

Third, the requirements that men had to fulfill to be included in
the study were strict. They included:

  • a sperm count of 15 million per milliliter, or 39 million per
    ejaculation (in two separate samples)
  • no sperm abnormalities or other problems
  • typical hormone levels
  • no serious diseases, psychiatric or otherwise
  • no signs of a sexually transmitted disease, either currently
    or in the past
  • a healthy prostate exam
  • a
    Body Mass Index
    of 20 to 32

Already, this may exclude quite a few perfectly “normal” men.

But now add in the study’s requirement for a the couple:

“a stable, mutually monogamous partnership for at least 1 year
was required, along with a coital frequency of twice/week on
average, an intent to remain in the relationship for the course
of the study, no desire for pregnancy within the next 2 years,
and willingness to accept a low but unknown risk of pregnancy.”

Another huge caveat was a major interruption of the study about 3
years in.

By late 2010, the side effects were becoming apparent; for
example, about 46% of men reported getting acne; 23% said the
injection site hurt, and 16% experienced muscle pain. (If you’re
one of the
4.5% of American women
who get injectable birth control, such

side effects
may seem all too
familiar
.)

There were also more serious side effects that were at least
“possibly” related to the injections, including “reports of mood
changes, depression, pain at the injection site, and increased
libido,” the researchers wrote in their study.

Two external boards of reviewers met frequently to go over the
study’s data and determine, ethically, if it should continue.

One review board in January 2011 told the researchers that they
could keep going.

In March 2011, however, the other review board told the
researchers to stop injections and move on to the recovery phase.
In particular, 3% of men in the study who said they experienced
depression troubled the latter review board.

For context, compare that the 30% of women who report
depression (plus other side effects) on female birth control, as
Lloyd told CNN. (Yes,
that rate is 10 times higher
.)

In their study, the researchers didn’t seem pleased with the
second board’s decision:

“It is well known from other trials of hormonal regimens in men
[…] that [adverse events] are reported frequently in these
longterm studies, even in a placebo group. That being said, 2
independent safety committees […] came to different conclusions
on the safety of the regimen, which resulted in early termination
of the study injections.”

The second group’s decision caused nearly 100 couples to stop
male birth control and resume female birth control.

Because of that interruption, plus the fact that you can’t
ethically give study volunteers a placebo or “fake” injection (a
lot of unplanned pregnancies would happen), “a definitive
answer as to whether the potential risks of this hormonal
combination for male contraception outweigh the potential
benefits cannot be made based on the present results,

they wrote (our emphasis added).

Still, the study’s authors said their work shows promise.

In addition to being effective, they noted more than 75% of
couples wanted to continue using the injections instead of female
birth control.

Male birth control is not ‘here’ — yet


time men last in bed thumbnails 04
Gene
Kim

Some outlets have teased that male birth control is here or
almost
here
.” And while it certainly seems within reach, it has been
a strange uphill battle — one that’s likely years away from any
kind of conclusion.

Until recently, most research into male birth control has focused
on animals like rodents. The results have been mixed, with some
early successes failing to translate to humans.

A 2015 study of two immune system-suppressing drugs, for example,
seemed to
decrease sperm mobility in mice
. But men who happened to be
taking one of the drugs at a properly scaled does were
still fertile
.

One reason for the dearth of research into male contraceptives is
that men have no known, natural cycle of infertility. In short,
the testicles are “always on” and making sperm, and well into old
age; pregnancy in women seemed like a more natural target for
contraception.

The social and historical context is crucial, too.

Until recently, most medical and scientific research was
performed by men. Contraception research of yesteryear, in
particular, focused primarily on women due to
a twisted mix
of misogyny,

racism
, gender
stereotyping
, and other problems.

Pharmaceutical companies should also accept some responsibility
for the slow pace. Even where certain male contraceptives showed
promise, for-profit ventures pulled their funding, presumably to
maintain a lucrative status quo, according to a 2008
study
.

And assuming a new male birth control (like
progestogen-testosterone shots) began clearing
the FDA’s rigorous three-phase drug approval process
today,
it could still be another 5 to 10 years before it arrives in
doctors’ offices or pharmacies, according to a September 2015
feature about male contraceptive research by Amber Cox
in Endocrine Today
.

The cost to develop and test a drug is also steep, typically

hundreds of millions of dollars
or sometimes billions, and
it’s no guarantee — it can fail FDA approval. In fact, about

86% of drugs don’t pass the FDA’s final two approval stages
.
(And that’s before considering the fact that 94% of all drugs
that pass initial animal trials fail to pass any of the three
human clinical trials.) Even if a drug does pass, it can show
weak results or turn up potential side effects that consumers
won’t be willing to risk in a medication.

So unless the injection passes future clinical drug trials to
show it’s safe and effective for a much larger and more diverse
population, the first male birth control is unfortunately still a
ways off.

Should progestogen-testosterone shots succeed, they may not be
enough to help all men:

“No single method is used universally by all women; in a way this
is analogous to the less than 5% of men who may not adequately
suppress their sperm output,” the author of one 2008 review of male
birth control research
wrote. “The need for a range of
different options is obvious because no single method can be
expected to be ideal for every couple.”

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Can strangers fall in love after asking each other 36 specific questions?

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Mitch and Greg from AsapSCIENCE sat down with Tech Insider to explain their experiment with the 36 questions. A study had found that these questions could create a bond between stranger strong enough, it could make them fall in love, and AsapSCIENCE put it to the test. 

Here’s the full list of 36 questions are below, and here are AsapSCIENCE videos on their YouTube channel.

Set I

1. Given the choice of anyone in the world, whom would you want as a dinner guest?

2. Would you like to be famous? In what way?

3. Before making a telephone call, do you ever rehearse what you are going to say? Why?

4. What would constitute a “perfect” day for you?

5. When did you last sing to yourself? To someone else?

6. If you were able to live to the age of 90 and retain either the mind or body of a 30-year-old for the last 60 years of your life, which would you want?

7. Do you have a secret hunch about how you will die?

8. Name three things you and your partner appear to have in common.

9. For what in your life do you feel most grateful?

10. If you could change anything about the way you were raised, what would it be?

11. Take four minutes and tell your partner your life story in as much detail as possible.

12. If you could wake up tomorrow having gained any one quality or ability, what would it be?

Set II

13. If a crystal ball could tell you the truth about yourself, your life, the future or anything else, what would you want to know?

14. Is there something that you’ve dreamed of doing for a long time? Why haven’t you done it?

15. What is the greatest accomplishment of your life?

16. What do you value most in a friendship?

17. What is your most treasured memory?

18. What is your most terrible memory?

19. If you knew that in one year you would die suddenly, would you change anything about the way you are now living? Why?

20. What does friendship mean to you?

21. What roles do love and affection play in your life?

22. Alternate sharing something you consider a positive characteristic of your partner. Share a total of five items.

23. How close and warm is your family? Do you feel your childhood was happier than most other people’s?

24. How do you feel about your relationship with your mother?

Set III

25. Make three true “we” statements each. For instance, “We are both in this room feeling …”

26. Complete this sentence: “I wish I had someone with whom I could share …”

27. If you were going to become a close friend with your partner, please share what would be important for him or her to know.

28. Tell your partner what you like about them; be very honest this time, saying things that you might not say to someone you’ve just met.

29. Share with your partner an embarrassing moment in your life.

30. When did you last cry in front of another person? By yourself?

31. Tell your partner something that you like about them already.

32. What, if anything, is too serious to be joked about?

33. If you were to die this evening with no opportunity to communicate with anyone, what would you most regret not having told someone? Why haven’t you told them yet?

34. Your house, containing everything you own, catches fire. After saving your loved ones and pets, you have time to safely make a final dash to save any one item. What would it be? Why?

35. Of all the people in your family, whose death would you find most disturbing? Why?

36. Share a personal problem and ask your partner’s advice on how he or she might handle it. Also, ask your partner to reflect back to you how you seem to be feeling about the problem you have chosen.

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